办公地点

我院205

办公电话

15243113936

邮箱

zhangxinmin@jlu.edu.cn

教育背景

2008-2010年 罗彻斯特大学 联合培养博士生 2007-2011年吉林大学 博士研究生 2004-2007 吉林大学 硕士研究生 2000-2004 吉林大学药学系 本科生

工作经历

2018-至今, 吉林大学, bat365官网登录入口, 副教授/硕士生导师

2010-2018, 吉林大学, bat365官网登录入口, 讲师

主讲课程

分子医学；生物工程下游技术； 组织工程

研究领域

使用酵母重组外源蛋白，研究基因表达及DNA复制调控机制

科研成果

1.CONG, Z., ZHAO, Q., YANG, B., CONG, D., ZHOU, Y., LEI, X. & ZHANG, X. 2020. Ginsenoside Rh3 Inhibits Proliferation and Induces Apoptosis of Colorectal Cancer Cells. Pharmacology, 105, 329-338.

2.LIU, J. H., SHI, Y. Y., TENG, S. Y., WU, L. P. & ZHANG, X. M. 2017. Establishment and Evaluation of a Loop-Mediated Isothermal Amplification Assay for Detection of Raccoon Dog in Meat Mixtures. Journal of Food Quality, 1-8.

3.TENG, S., WANG, Y., LI, P., LIU, J., WEI, A., WANG, H., MENG, X., PAN, D. & ZHANG, X. 2017. Effects of R type and S type ginsenoside Rg3 on DNA methylation in human hepatocarcinoma cells. Mol Med Rep, 15, 2029-2038.

4.WANG, H. T., ZHANG, X. M., KONG, N., WEI, A. H., ZHANG, Y. H., MA, J., ZHOU, Y. L. & YAN, W. Q. 2014. Expression, purification and characterization of a recombinant Tat47-57-Oct4 fusion protein in Pichia pastoris. Molecular Medicine Reports, 9, 471-475.

5.YU, Q., OLSEN, L., ZHANG, X., BOEKE, J. D. & BI, X. 2011a. Differential contributions of histone H3 and H4 residues to heterochromatin structure. Genetics, 188, 291-308.

6.YU, Q., ZHANG, X. & BI, X. 2011b. Roles of chromatin remodeling factors in the formation and maintenance of heterochromatin structure. J Biol Chem, 286, 14659-69.

7.ZHANG, X. M., YU, Q., OLSEN, L. & BI, X. 2012. Functions of Protosilencers in the Formation and Maintenance of Heterochromatin in Saccharomyces cerevisiae. Plos One, 7.